Foxdale caused the shock of the day in the GH Corlett Woods Cup preliminary round.
A last-gasp winner from Charlie Harrison ensured they defeated promotion chasing Ramsey Youth Centre.
In a see-saw cup tie at Billy Goat Park, the hosts led and then twice fought from behind before grabbing a 90th minute victory.
Harrison had earlier grabbed his first and was joined on the scoresheet by Ricky Newsome and player manager Steve Betteridge.
Youth Centre, who led 3-2 at half-time, also had a penalty saved.
Braddan also caused a bit of a surprise with a 3-1 home success over Castletown, courtesy of a Daniel Bedford double - one from the penalty spot - and Kian Geoghan.
Ashley Sansbury scored for Town from the spot.
Jordan Primrose Smith and Adam Fretwell earned Colby a hard-fought 2-1 win over Pulrose United, who replied through Ben Cowin.
Three quick-fire goals at the start of the second half booked Douglas Athletic their spot in the last eight.
Andy Glover had headed the southerners in front before the break but Kyle Berry, Connor Dowell and John McMullin turned the tie on its head early in the second half.
Dean Kinley pulled one back for Malew but they couldn’t prevent the Division Two leaders progressing.
Douglas Royal thrashed Onchan 9-2 at Ballafletcher.
And there was no doubting the star of the show.
Craig Dolman hit a double hat-trick with six in the romp and was joined on the scoresheet by Paul Whitley who netted a treble of his own.
Rob Callow and Rob Byrne found the net for Onchan on a day to forget for the visitors.