With the Isle of Man players back with their clubs after representing England in the UEFA Regions Cup in Slovakia, there's a full Premier League fixture list on Saturday afternoon.
Leaders Old Boys don't play which gives second placed Ramsey the chance to move to the top.
The northerners make the trip to Port Erin needing a win against Rushen to move to the summit.
Champions St. George's return to action with a home game against Gymns and Peel play for the first time in several weeks when they welcome Laxey to Douglas Road.
Ayre are the visitors to The Bowl to face St. Mary's, Michael host St. John's and Union Mills aim to break their duck with a home encounter with Corinthians.