Ramsey could all but seal Rugby's Manx Shield title if they beat rivals Vagabonds "B" at Glencrutchery Road on Saturday afternoon.
The northerners are unbeaten this season and have already defeated Vagas in the corresponding fixture.
In Football, the top three sides in Division Two should all progress from their quater-final ties.
Corinthians are at home to Onchan, Old Boys travel to Ronaldsway and Michael entertain Castletown. In the other game, Police tackle Foxdale.
Division One leaders St. George's aim to preserve their eight point advantage at the top with a home game against Douglas Royal. At the bottom, there's a big relegation encounter between Marown and Union Mills.
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